Dr. Wilson earned both his MD and PhD from the University of Chicago in 1972 and trained at Boston Floating Hospital, National Institutes of Health, and the University of Michigan. His PhD in biochemistry and fellowship in medical genetics led him to combine research and scholarship with clinical care, early NIH grants and pioneering cloning of human DNA combined with interest in dysmorphology to yield over 200 articles and several books. He has served as an endowed full professor of pediatrics at UT Southwestern and continues to teach and provide clinical correlation of DNA results at Texas Tech University Health Sciences Center in Lubbock.

Dr. Wilson has conducted over 27,000 primary medical genetic evaluations and another 20,000 in general pediatrics. Most of that time involved a general focus on causes of intellectual disability/autism and birth defect patterns (syndromes). These encounters led to his book Surprised by Joy: Mothers Stories of Child Disability that has now been reissued through KDP Amazon. In 2011 he began a specific focus on hypermobility syndromes and Ehlers-Danlos syndrome, realizing that these patients–85% female—receive partial diagnoses like chronic fatigue syndrome, fibromyalgia, or anxiety disorder. He developed an evidence-based model for recognizing EDS through systematic symptom documentation and clinical correlation of DNA sequencing results. Pivotal in these studies has been the recognition of dysautonomia as a reciprocal and inevitable consequence of tissue-vessel laxity, its manifestations as POTS, MCAS, and IBS among the most treatable of EDS. Study of over 2000 EDS patients, 532 of them having gene changes by whole exome sequencing, led to another KDP Amazon publication: The DNA of Ehlers-Danlos and Long COVID19 Syndromes: Healing Their Flexibility, Fatigue, and Fear.